Product Info Summary
SKU: | A11226 |
---|---|
Size: | 100μl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-CD300e/Lmir6 Antibody
View all CD300e/LMIR6 Antibodies
SKU/Catalog Number
A11226
Size
100μl
Form
Liquid
Description
Boster Bio Anti-CD300e/Lmir6 Antibody catalog # A11226. Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CD300e/Lmir6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11226)
Host
Rabbit
Contents
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality
Polyclonal
Clone Number
3A8
Isotype
IgG
Immunogen
Synthetic peptide from human protein at AA range: 31-80.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A11226 is reactive to Cd300e in Human
Applications
A11226 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
21.822kDa
Background of CD300e/LMIR6
Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).
Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.
Valtorta, F. et al. (2004) Bioessays 26, 445-53.
Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.
Bonanomi, D. et al. (2007) Biochem J 404, 525-34.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-P, 1:50-300
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.
Click image to see more details
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.
Protein Target Info & Infographic
Gene/Protein Information For Cd300e (Source: Uniprot.org, NCBI)
Gene Name
Cd300e
Full Name
CMRF35-like molecule 2
Weight
21.822kDa
Superfamily
CD300 family
Alternative Names
CD300 antigen like family member E; CD300 antigen-like family member E; CD300e antigenPIgR-2; CD300e molecule; CD300e; CD300LE; CD300LEPIgR2; CLM2; CLM-2; CLM2CMRF35-A5; CMRF35A5; CMRF35-like molecule 2; Immune receptor expressed on myeloid cells 2; IREM-2; IREM2IREM-2; LMIR6; Poly-Ig receptor 2; Polymeric immunoglobulin receptor 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cd300e, check out the Cd300e Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cd300e: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD300e/Lmir6 Antibody (A11226)
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No publications found for A11226
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Customer Reviews
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Customer Q&As
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Find answers in Q&As, reviews.
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7 Customer Q&As for Anti-CD300e/Lmir6 Antibody
Question
Is a blocking peptide available for product anti-CD300e/Lmir6 antibody (A11226)?
Verified Customer
Verified customer
Asked: 2020-02-04
Answer
We do provide the blocking peptide for product anti-CD300e/Lmir6 antibody (A11226). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2020-02-04
Question
My question regards to test anti-CD300e/Lmir6 antibody A11226 on human peripheral blood monocyte for research purposes, then I may be interested in using anti-CD300e/Lmir6 antibody A11226 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2019-12-20
Answer
The products we sell, including anti-CD300e/Lmir6 antibody A11226, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2019-12-20
Question
I was wanting to use your anti-CD300e/Lmir6 antibody for IHC for human peripheral blood monocyte on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human peripheral blood monocyte identification?
Verified Customer
Verified customer
Asked: 2019-07-09
Answer
You can see on the product datasheet, A11226 anti-CD300e/Lmir6 antibody has been tested for IHC on human tissues. We have an innovator award program that if you test this antibody and show it works in human peripheral blood monocyte in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-07-09
Question
We are currently using anti-CD300e/Lmir6 antibody A11226 for human tissue, and we are satisfied with the IHC results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on horse tissues as well?
Verified Customer
Verified customer
Asked: 2018-05-23
Answer
The anti-CD300e/Lmir6 antibody (A11226) has not been validated for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2018-05-23
Question
Does A11226 anti-CD300e/Lmir6 antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?
M. Johnson
Verified customer
Asked: 2018-02-13
Answer
You can see on the product datasheet, A11226 anti-CD300e/Lmir6 antibody as been tested on IHC. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.
Boster Scientific Support
Answered: 2018-02-13
Question
I see that the anti-CD300e/Lmir6 antibody A11226 works with IHC, what is the protocol used to produce the result images on the product page?
Verified Customer
Verified customer
Asked: 2018-01-30
Answer
You can find protocols for IHC on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2018-01-30
Question
Is this A11226 anti-CD300e/Lmir6 antibody reactive to the isotypes of CD300E?
N. Banerjee
Verified customer
Asked: 2013-08-15
Answer
The immunogen of A11226 anti-CD300e/Lmir6 antibody is Synthetic peptide from human protein at AA range: 31-80. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2013-08-15