Anti-CDK5RAP2 Antibody

Product Name

Anti-CDK5RAP2 Antibody

View all CDK5RAP2 Antibodies

SKU/Catalog Number

A03102

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CDK5RAP2 Antibody (Catalog# A03102). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Storage & Handling

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CDK5RAP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03102)

Host

Rabbit

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

7A7

Isotype

Rabbit IgG

Immunogen

A peptide derived from human CDK5RAP2. Immunogen sequence location: 251-300

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03102 is reactive to CDK5RAP2 in Human, Mouse, Rat

Applications

A03102 is guaranteed for ELISA, IHC-P, IF (paraffin) Boster Guarantee

Observed Molecular Weight

72 kDa

Calculated molecular weight

215.038kDa

Background of CDK5RAP2

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry, 1:100 - 1:300
ELISA, 1:20000
Not yet tested in other applications.

Validation Images & Assay Conditions

Click image to see more details

Immunohistochemistry analysis of paraffin-embedded human brain, using CDK5RAP2 Antibody. The picture on the right is blocked with the synthesized peptide.

Gene/Protein Information For CDK5RAP2 (Source: Uniprot.org, NCBI)

Alternative Names

C48; CDK5 activator-binding protein C48; CDK5 regulatory subunit associated protein 2; CDK5 regulatory subunit-associated protein 2; centrosomal protein 215 kDa; Centrosome-associated protein 215; Cep215; DKFZp686B1070; DKFZp686D1070; FLJ10867; KIAA1633microcephaly, primary autosomal recessive 3; MCPH3 CDK5RAP2 C48, Cep215, MCPH3 CDK5 regulatory subunit associated protein 2 CDK5 regulatory subunit-associated protein 2|CDK5 activator-binding protein C48|centrosomal protein 215 kDa|centrosomin

For more info on CDK5RAP2, check out the CDK5RAP2 Infographic

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In this infographic, you will see the following information for CDK5RAP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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