Anti-CDK8 Antibody Picoband™

CDK8 antibody

Boster Bio Anti-CDK8 Antibody Picoband™ catalog # A01493-1. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A01493-1
Size: 100μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-CDK8 Antibody Picoband™

View all CDK8 Antibodies

SKU/Catalog Number

A01493-1

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CDK8 Antibody Picoband™ catalog # A01493-1. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CDK8 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01493-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

E. coli-derived human Cdk8 recombinant protein (K355-Y464).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

A01493-1 is reactive to CDK8 in Human

Applications

A01493-1 is guaranteed for ELISA, WB Boster Guarantee

Background of CDK8

Cell division protein kinase 8 is an enzyme that in humans is encoded by the CDK8 gene. It is mapped to 13q12.13. This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Direct ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For CDK8 (Source: Uniprot.Org, NCBI)

Uniprot ID

P49336

Gene ID

1024

Gene Name

CDK8

Full Name

Cyclin-dependent kinase 8

Weight

53.284kDa

Superfamily

protein kinase superfamily

Alternative Names

CDK8 protein kinase; CDK8; Cell division protein kinase 8; cyclin-dependent kinase 8; EC 2.7.11; EC 2.7.11.22; EC 2.7.11.23; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; Protein kinase K35 CDK8 IDDHBA, K35 cyclin dependent kinase 8 cyclin-dependent kinase 8|CDK8 protein kinase|cell division protein kinase 8|mediator complex subunit CDK8|mediator of RNA polymerase II transcription subunit CDK8|protein kinase K35

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on CDK8, check out the CDK8 Infographic

CDK8 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for CDK8: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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1 Customer Q&As for Anti-CDK8 Antibody Picoband™

Question

We are currently using anti-CDK8 antibody A01493-1 for human tissue, and we are well pleased with the ELISA results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on bovine tissues as well?

Verified Customer

Verified customer

Asked: 2019-08-05

Answer

The anti-CDK8 antibody (A01493-1) has not been tested for cross reactivity specifically with bovine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-08-05

Size

Conjugation

how to order through PO

Total: $315

Size:100μg

SKU:A01493-1

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Boster offers all the reagents you need for your immunostaining and western blotting experiments. We've got everything from buffers to lysates to kits, including our popular and well-cited BCA, CCK-8, and MTT assay kits.

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A01493-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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