Product Info Summary
SKU: | M08014 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Mouse |
Application: | ICC, WB |
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Product info
Product Name
Anti-CHRDL1 monoclonal Antibody
View all Chordin-like 1/CHRDL1 Antibodies
SKU/Catalog Number
M08014
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CHRDL1 monoclonal Antibody catalog # M08014. Tested in WB,ICC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CHRDL1 monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M08014)
Host
Mouse
Contents
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Monoclonal
Clone Number
Clone: 22C5.H7.A6 IgG2a kappa
Isotype
IgG2a kappa
Immunogen
Anti-Esrp-2 is produced by repeated immunizations of full length recombinant mouse Esrp-2 fusion protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M08014 is reactive to Chrdl1 in Human, Mouse, Rat
Applications
M08014 is guaranteed for ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
50.732kDa
Background of Chordin-like 1/CHRDL1
Epithelial splicing regulatory protein 2 (Esrp-2) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Esrp-2 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
ICC: 1:300
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For Chrdl1 (Source: Uniprot.org, NCBI)
Gene Name
Chrdl1
Full Name
Chordin-like protein 1
Weight
50.732kDa
Alternative Names
CHL; Chordin-like 1; chordin-like protein 1; CHRDL1; CRDL1; dA141H5.1; Neuralin 1; neuralin-1; neurogenesin-1; NRLN1; NRLN1neuralin 1; Ventroptin alpha; ventroptin; VOPT Chrdl1|CHL, CHL1, N, Nrln1, V, VOPT|chordin-like 1|chordin-like protein 1|neuralin-1|neurogenesin-1|ventroptin-alpha|ventroptin-beta
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Chrdl1, check out the Chrdl1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Chrdl1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CHRDL1 monoclonal Antibody (M08014)
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No publications found for M08014
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