Product Info Summary
SKU: | M01797 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Mouse |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-CIB1 Monoclonal Antibody
SKU/Catalog Number
M01797
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CIB1 Monoclonal Antibody catalog # M01797. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CIB1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01797)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
5A1F5E12 / 5A1H7E12
Isotype
IgG
Immunogen
Purified recombinant fragment of CIB1 expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01797 is reactive to CIB1 in Human
Applications
M01797 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
21.703kDa
Background of CIB1
Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of CIB1 using Anti-CIB1 Monoclonal Antibody (M01797).
Immunohistochemistry (IHC) analysis of paraffin-embedded human thalamus (left) and glioma (right) tissueClick image to see more details
Figure 1. Western blotting validation for Anti-CIB1 Monoclonal Antibody M01797
Western Blot (WB) analysis using CIB1 Monoclonal Antibody against truncated CIB1 recombinant protein (1) and A431 cell lysate (2).Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CIB1 (Source: Uniprot.org, NCBI)
Gene Name
CIB1
Full Name
Calcium and integrin-binding protein 1
Weight
21.703kDa
Alternative Names
calcium and integrin binding 1 (calmyrin); Calcium- and integrin-binding protein; Calmyrin; CIB1; CIBcalcium and integrin binding protein; CIBP; DNA-dependent protein kinase interacting protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; KIP1; KIPcalcium and integrin binding, protein kinase interacting protein; PRKDCIP; SIP2-28; SIP2-28calcium and integrin-binding protein 1; Snk interacting protein 2-28; SNK-interacting protein 2-28 CIB1 CIB, CIBP, KIP1, PRKDCIP, SIP2-28 calcium and integrin binding 1 calcium and integrin-binding protein 1|DNA-PK interaction protein|DNA-PKcs-interacting protein|DNA-dependent protein kinase interacting protein|SNK-interacting protein 2-28|calcium and integrin binding 1 (calmyrin)|testicular secretory protein Li 9
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CIB1, check out the CIB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CIB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CIB1 Monoclonal Antibody (M01797)
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No publications found for M01797
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Customer Reviews
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