Product Info Summary
SKU: | A09846 |
---|---|
Size: | 100ul |
Reactive Species: | Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Claudin-8 CLDN8 Antibody
SKU/Catalog Number
A09846
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Claudin-8 CLDN8 Antibody catalog # A09846. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Claudin-8 CLDN8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09846)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human EFNA2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09846 is reactive to CLDN8 in Mouse, Rat
Applications
A09846 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
24.845kDa
Background of Claudin-8
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis By similarity.
Cerretti D.P., Genomics 47:131-135(1998).
Aasheim H.C., Biochem. Biophys. Res. Commun. 252:378-382(1998).
Grimwood J., Nature 428:529-535(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Claudin-8 CLDN8 Antibody A09846
Western blot analysis of extract of various cellsProtein Target Info & Infographic
Gene/Protein Information For CLDN8 (Source: Uniprot.org, NCBI)
Gene Name
CLDN8
Full Name
Claudin-8
Weight
24.845kDa
Superfamily
claudin family
Alternative Names
claudin 8; Claudin8; Claudin-8; CLDN8; human CLDN8 gene for claudin-810claudin-8 CLDN8 HEL-S-79 claudin 8 claudin-8|epididymis secretory protein Li 79
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CLDN8, check out the CLDN8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CLDN8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Claudin-8 CLDN8 Antibody (A09846)
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No publications found for A09846
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