Claudin-8 Antibodies

AND CLDN8 ELISA kits, Claudin-8 Proteins

Many biological assays use antibodies to detect Claudin-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Claudin-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Claudin-8 antibodies...

We validate the specificity of these antibodies to Claudin-8 by testing them on tissues known to express CLDN8 positively and negatively. Browse below to find the CLDN8 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLDN8 Infographic by Boster Bio

All CLDN8 Products

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Specificity

Applications

Price

Anti-Claudin-8 CLDN8 Antibody

Western blot analysis of extracts of various cell lines, using CLDN17 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded mouse kidney using CLDN17 antibody at dilution of 1:100

Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A09846
100ul

Anti-Claudin-8 CLDN8 Antibody

Western blot analysis of lysates from Jurkat cells, using CLDN8 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A09846-1
100ul

Claudin 8 (CLDN8) (NM_199328) Human Over-expression Lysate

Human

$628
Cat # LS009073
20 µg, 100 µg

CLDN8 Overview

Facts about Claudin-8.

CLDN8 3D structure. Source: alphafold

Claudin-8 (CLDN8)

Tight-junction protein required for paracellular chloride transport in the kidney. Mediates recruiting of CLDN4 to tight junction in the kidney.

Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. .

Gene Information

Human
Gene Name:	CLDN8
Uniprot:	P56748
Entrez:	9073

Family

Belongs to:

claudin family

Alternative Names

claudin 8; Claudin8; Claudin-8; CLDN8; human CLDN8 gene for claudin-810claudin-8

Molecular Weight

Mass (kDA):
24.845 kDA

Genomic Context


Human

Location:	21q22.11
Sequence:	21; NC_000021.9 (30214006..30216097, complement)

Tissue Specificity

Expressed in the epididymis, mainly in the caput segment.

Subcellular Localizations

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells.