Anti-CLD14 CLDN14 Antibody

Product Name

Anti-CLD14 CLDN14 Antibody

View all Claudin-14 Antibodies

SKU/Catalog Number

A06550

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CLD14 CLDN14 Antibody catalog # A06550. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CLD14 CLDN14 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06550)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human LS14A protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06550 is reactive to CLDN14 in Human, Mouse

Applications

A06550 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

25.699kDa

Background of Claudin-14

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Marino G., J. Biol. Chem. 278:3671-3678(2003).
Kabeya Y., J. Cell Sci. 117:2805-2812(2004).
Ross M.T., Nature 434:325-337(2005

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000
ELISA 1:5000-20000

Validation Images & Assay Conditions

Click image to see more details

Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°C over night

Gene/Protein Information For CLDN14 (Source: Uniprot.org, NCBI)

Alternative Names

claudin 14; Claudin14; Claudin-14; CLDN14; DFNB29; human CLDN14 gene10claudin-14 CLDN14 DFNB29 claudin 14 claudin-14

For more info on CLDN14, check out the CLDN14 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CLDN14: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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