Product Info Summary
SKU: | A00686-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC |
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Product info
Product Name
Anti-Copper-transporting ATPase 2 ATP7B Antibody
SKU/Catalog Number
A00686-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Copper-transporting ATPase 2 ATP7B Antibody catalog # A00686-1. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Copper-transporting ATPase 2 ATP7B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00686-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ATP7B
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00686-1 is reactive to ATP7B in Human, Mouse, Rat
Applications
A00686-1 is guaranteed for ELISA, IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
157.263kDa
Background of ATP7B
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Denis Tvorogov, J. Cell Sci., Feb 2005; 118: 601 - 610.
Brenda J. Irvin, Mol. Cell. Biol., Dec 2000; 20: 9149 - 9161.
Benoit Poulin, J. Biol. Chem., Feb 2000; 275: 6411.
Ichiro Nakamura, J. Cell Biol., Jan 2001; 152: 361.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ATP7B (Source: Uniprot.org, NCBI)
Gene Name
ATP7B
Full Name
Copper-transporting ATPase 2
Weight
157.263kDa
Superfamily
cation transport ATPase (P-type) (TC 3.A.3) family
Alternative Names
ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; Copper pump 2; copper-transporting ATPase 2; EC 3.6.3; EC 3.6.3.4; PWD; WC1; WD; Wilson disease-associated protein; WNDATPase, Cu++ transporting, beta polypeptide (Wilson disease) ATP7B PWD, WC1, WD, WND ATPase copper transporting beta copper-transporting ATPase 2|ATPase, Cu(2+)- transporting, beta polypeptide|ATPase, Cu++ transporting, beta polypeptide|Wilson disease-associated protein|copper pump 2|copper-transporting protein ATP7B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ATP7B, check out the ATP7B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ATP7B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Copper-transporting ATPase 2 ATP7B Antibody (A00686-1)
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No publications found for A00686-1
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