Anti-CTSC Antibody Picoband™

Cathepsin C/DPPI antibody

Boster Bio Anti-CTSC Antibody Picoband™ catalog # A02136-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A02136-2
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, Flow Cytometry, WB

Product Name

Anti-CTSC Antibody Picoband™

View all Cathepsin C/DPPI Antibodies

SKU/Catalog Number

A02136-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CTSC Antibody Picoband™ catalog # A02136-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-CTSC Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02136-2)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Immunogen

E.coli-derived human CTSC recombinant protein (Position: V22-L463).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02136-2 is reactive to CTSC in Human

Applications

A02136-2 is guaranteed for ELISA, Flow Cytometry, WB Boster Guarantee

Background of Cathepsin C/DPPI

Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. In humans, it is encoded by the CTSC gene. This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry, 1-3 μg/1x10^6 cells, Human
Direct ELISA, 0.1-0.5 μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For CTSC (Source: Uniprot.Org, NCBI)

Uniprot ID

P53634

Gene ID

1075

Gene Name

CTSC

Full Name

Dipeptidyl peptidase 1

Weight

51.854kDa

Superfamily

peptidase C1 family

Alternative Names

Cathepsin C; cathepsin CEC 3.4.14.1; Cathepsin J; CPPIHMS; CTSC; dipeptidyl peptidase 1; Dipeptidyl peptidase I; Dipeptidyl transferase; dipeptidyl-peptidase I; DPP1; DPPI; DPP-I; JP; JPD; PALS; PLS CTSC CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS cathepsin C dipeptidyl peptidase 1|cathepsin J|dipeptidyl transferase|dipeptidyl-peptidase I

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on CTSC, check out the CTSC Infographic

CTSC infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for CTSC: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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Conjugation

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Size

Total: $315

Size:100 μg

SKU:A02136-2

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A02136-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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