Product Info Summary
| SKU: | A05286 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CTTNBL1 CTNNBL1 Antibody
SKU/Catalog Number
A05286
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CTTNBL1 CTNNBL1 Antibody (Catalog # A05286). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CTTNBL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CTTNBL1 CTNNBL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05286)
Host
Rabbit
Contents
CTTNBL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CTTNBL1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human CTTNBL1. The immunogen is located within the last 50 amino acids of CTTNBL1.
Cross-reactivity
CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist; this antibody will detect all but isoform b.
Reactive Species
A05286 is reactive to CTNNBL1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
65.2 kDa
Background of CTNNBL1
The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05286 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CTTNBL1 antibody can be used for detection of CTTNBL1 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CTNNBL1 in human brain tissue lysate with CTNNBL1 antibody at 0.5 μg/mL.
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Immunohistochemistry of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 5 μg/mL.
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Immunofluorescence of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 20 μg/mL.
Specific Publications For Anti-CTTNBL1 CTNNBL1 Antibody (A05286)
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