Product Info Summary
SKU: | A03670 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Cubilin CUBN Antibody
SKU/Catalog Number
A03670
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Cubilin CUBN Antibody catalog # A03670. Tested in WB,IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cubilin CUBN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03670)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human KCNQ4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03670 is reactive to CUBN in Human
Applications
A03670 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
398.736kDa
Background of Cubilin
Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.
Kubisch C., Cell 96:437-446(1999).
Gregory S.G., Nature 441:315-321(2006).
Selyanko A.A., J. Physiol. (Lond.) 522:349-355(2000).<
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cubilin antibody. Counter stained with hematoxylin.
Protein Target Info & Infographic
Gene/Protein Information For CUBN (Source: Uniprot.org, NCBI)
Gene Name
CUBN
Full Name
Cubilin
Weight
398.736kDa
Alternative Names
cubilin; cubilin (intrinsic factor-cobalamin receptor); Cubilin; CUBN; Cubulin; gp280; IFCR; MGA1 CUBN IFCR, IGS, IGS1, MGA1, gp280 cubilin cubilin|460 kDa receptor|cubilin (intrinsic factor-cobalamin receptor)|cubilin precursor variant 1|cubilin precursor variant 2|cubilin precursor variant 3|intestinal intrinsic factor receptor|intrinsic factor-vitamin B12 receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CUBN, check out the CUBN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CUBN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cubilin CUBN Antibody (A03670)
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No publications found for A03670
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