Anti-Cystathionase/CTH Antibody Picoband™

Cystathionase antibody

Boster Bio Anti-Cystathionase/CTH Antibody Picoband™ catalog # PB9494. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 6 publication(s).

Product Info Summary

SKU: PB9494
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-Cystathionase/CTH Antibody Picoband™

View all Cystathionase Antibodies

SKU/Catalog Number

PB9494

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Cystathionase/CTH Antibody Picoband™ catalog # PB9494. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cystathionase/CTH Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9494)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human Cystathionase recombinant protein (Position: D181-H398). Human Cystathionase shares 85.8% amino acid (aa) sequence identity with both mouse and rat Cystathionase.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9494 is reactive to CTH in Human, Mouse, Rat

Applications

PB9494 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

45 kDa

Calculated molecular weight

44.508kDa

Background of Cystathionase

Cystathionine gamma-lyase (or cystathionase) is an enzyme which breaks down cystathionine into cysteine and α-ketobutyrate. The International Radiation Hybrid Mapping Consortium mapped the CTH gene to chromosome 1. The CTH gene had earlier been assigned to chromosome 16 by study of somatic cell hybrids. It is demonstrated that hydrogen sulfide (H2S) is physiologically generated by CTH.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For CTH (Source: Uniprot.org, NCBI)

Gene Name

CTH

Full Name

Cystathionine gamma-lyase

Weight

44.508kDa

Superfamily

trans-sulfuration enzymes family

Alternative Names

cystathionase (cystathionine gamma-lyase); cystathionine gamma-lyase; cysteine desulfhydrase; EC 4.4.1; EC 4.4.1.1; gamma-cystathionase; homoserine deaminase; homoserine dehydratase; MGC9471 CTH cystathionine gamma-lyase cystathionine gamma-lyase|cystathionase (cystathionine gamma-lyase)|cysteine desulfhydrase|cysteine-protein sulfhydrase|gamma-cystathionase|homoserine deaminase|homoserine dehydratase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CTH, check out the CTH Infographic

CTH infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CTH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9494 has been cited in 6 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Nie L,Liu M,Chen J,Wu Q,Li Y,Yi J,Zheng X,Zhang J,Chu C,Yang J.Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway.Mol Med Rep.2021 Apr;23(4):299.doi:10.3892/mmr.2021.11938.Epub 2021 Mar 2.PMID:336498
Species: Rat
PB9494 usage in article: APP:WB, SAMPLE:VENTRICULAR TISSUE, DILUTION:1:500

High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways

Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats

Endogenous carbon monoxide downregulates hepatic cystathionine-?-lyase in rats with liver cirrhosis

Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats

Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway

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1 Customer Q&As for Anti-Cystathionase/CTH Antibody Picoband™

Question

We are currently using anti-Cystathionase/CTH antibody PB9494 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on primate tissues as well?

Verified Customer

Verified customer

Asked: 2019-10-03

Answer

The anti-Cystathionase/CTH antibody (PB9494) has not been tested for cross reactivity specifically with primate tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-10-03

Order DetailsPrice
PB9494

100μg

$370
PB9494-10ug

10μg sample (liquid)

$99
PB9494-Biotin

100 μg Biotin conjugated

$570
PB9494-Cy3

100 μg Cy3 conjugated

$570
PB9494-Dylight488

100 μg Dylight488 conjugated

$570
PB9494-Dylight550

100 μg Dylight550 conjugated

$570
PB9494-Dylight594

100 μg Dylight594 conjugated

$570
PB9494-FITC

100 μg FITC conjugated

$570
PB9494-HRP

100 μg HRP conjugated

$570
PB9494-APC

100 μg APC conjugated

$670
PB9494-PE

100 μg PE conjugated

$670
PB9494-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9494
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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