Anti-DAP12 Rabbit Monoclonal Antibody

Product Name

Anti-DAP12 Rabbit Monoclonal Antibody

View all DAP12 Antibodies

SKU/Catalog Number

M01996-1

Size

100 μl/vial

Form

Liquid

Description

Boster Bio Anti-DAP12 Rabbit Monoclonal Antibody catalog # M01996-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DAP12 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01996-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

19T88

Isotype

IgG

Immunogen

A synthesized peptide derived from human DAP12

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01996-1 is reactive to TYROBP in Human

Applications

M01996-1 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

12 kDa

Calculated molecular weight

12.179kDa

Background of DAP12

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:80

Validation Images & Assay Conditions

Click image to see more details

Western blot analysis of DAP12 expression in Human PBMC cell lysate.

Gene/Protein Information For TYROBP (Source: Uniprot.org, NCBI)

Alternative Names

DAP12; DAP12PLOSL; DNAX-activation protein 12; KARAP; KARAPPLO-SL; KAR-associated protein; killer activating receptor associated protein; Killer-activating receptor-associated protein; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; TYROBP TYROBP DAP12, KARAP, PLOSL, PLOSL1 transmembrane immune signaling adaptor TYROBP TYRO protein tyrosine kinase-binding protein|DNAX adaptor protein 12|DNAX-activation protein 12|KAR-associated protein|TYRO protein tyrosine kinase binding protein|killer-activating receptor-associated protein|polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy

For more info on TYROBP, check out the TYROBP Infographic

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In this infographic, you will see the following information for TYROBP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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