Anti-DDIT4L Purified Monoclonal Antibody

Product Name

Anti-DDIT4L Purified Monoclonal Antibody

View all DDIT4L Antibodies

SKU/Catalog Number

M09701

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-DDIT4L Purified Monoclonal Antibody (Catalog# M09701). Tested in Flow Cytometry, WB application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-DDIT4L Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M09701)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

DDIT-03

Isotype

Mouse IgG1

Immunogen

N-terminal recombinant fragment of human DDIT4L (amino acids 2-98). The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.

Cross-reactivity

As in case with other anti-CD170 antibodies, this antibody cross-reacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.

Reactive Species

M09701 is reactive to DDIT4L in Human

Observed Molecular Weight

42 kDa

Calculated molecular weight

21.7 kDa

Background of DDIT4L

DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M09701 is guaranteed for Flow Cytometry, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml. Intracellular staining.

Validation Images & Assay Conditions

See full target information DDIT4L

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