Anti-DECR1 Antibody

Product Name

Anti-DECR1 Antibody

View all DECR1 Antibodies

SKU/Catalog Number

A07482

Size

100ul

Form

Liquid

Description

Boster Bio Anti-DECR1 Antibody catalog # A07482. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DECR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07482)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human p52 S6 kinase

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07482 is reactive to DECR1 in Human, Mouse, Rat

Applications

A07482 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

36.068kDa

Background of DECR1

Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.

Nakajima D., DNA Res. 9:99-106(2002).
Olsen J.V., Cell 127:635-648(2006).
Hirosawa M., DNA Res. 6:329-336(1999).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-DECR1 Antibody A07482

Western blot analysis of extracts of various cell lines

Gene/Protein Information For DECR1 (Source: Uniprot.org, NCBI)

Alternative Names

2,4-dienoyl CoA reductase 1, mitochondrial; 4-enoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase; DECR; DECR1; DECR2,4-dienoyl-CoA reductase [NADPH]2,4-dienoyl-CoA reductase, mitochondrial; EC 1.3.1.34; NADPH; SDR18C1; short chain dehydrogenase/reductase family 18C, member 1 DECR1 DECR, NADPH, SDR18C1 2,4-dienoyl-CoA reductase 1 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial|2,4-dienoyl-CoA reductase 1, mitochondrial|2,4-dienoyl-CoA reductase, mitochondrial|4-enoyl-CoA reductase|short chain dehydrogenase/reductase family 18C member 1

For more info on DECR1, check out the DECR1 Infographic

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In this infographic, you will see the following information for DECR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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