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Product Info Summary
| SKU: | A31772 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-DELE DELE1 Antibody
SKU/Catalog Number
A31772
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DELE DELE1 Antibody (Catalog # A31772). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Rat.
Storage & Handling
DELE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-DELE DELE1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A31772)
Host
Rabbit
Contents
DELE Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
It is predicted to not cross-react with other members of the cavin family.
Reactive Species
A31772 is reactive to DELE1 in Human, Rat
Applications
A31772 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
55.92kDa
Background of DELE1
DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DELE antibody can be used for detection of DELE by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DELE in rat brain tissue lysate with DELE antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of DELE in human brain tissue with DELE antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For DELE1 (Source: Uniprot.org, NCBI)
Gene Name
DELE1
Full Name
DAP3-binding cell death enhancer 1
Weight
55.92kDa
Alternative Names
DAP3-binding cell death enhancer 1 DELE1 DELE(L), KIAA0141, DELE1 DAP3 binding cell death enhancer 1 death ligand signal enhancer|DAP3-binding cell death enhancer 1, long form
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DELE1, check out the DELE1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DELE1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DELE DELE1 Antibody (A31772)
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No publications found for A31772
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Customer Reviews
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