Anti-DNA ligase 3 LIG3 Antibody

DNA Ligase III antibody

Boster Bio Anti-DNA ligase 3 LIG3 Antibody catalog # A02741-1. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A02741-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, ICC, WB

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Product Name

Anti-DNA ligase 3 LIG3 Antibody

View all DNA Ligase III Antibodies

SKU/Catalog Number

A02741-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-DNA ligase 3 LIG3 Antibody catalog # A02741-1. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DNA ligase 3 LIG3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02741-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human NFATc3 around the phosphorylation site of S165.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02741-1 is reactive to LIG3 in Human, Mouse, Rat

Applications

A02741-1 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

112.907kDa

Background of DNA Ligase III

Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Burd C.G., Proc. Natl. Acad. Sci. U.S.A. 86:9788-9792(1989).
Swanson M.S., Mol. Cell. Biol. 7:1731-1739(1987).
Merrill B.M., Nucleic Acids Res. 17:8441-8449(1989).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For LIG3 (Source: Uniprot.org, NCBI)

Gene Name

LIG3

Full Name

DNA ligase 3

Weight

112.907kDa

Superfamily

ATP-dependent DNA ligase family

Alternative Names

DNA ligase 3; DNA ligase III; EC 6.5.1.1; LIG2; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; Polydeoxyribonucleotide synthase [ATP] 3 LIG3 LIG2alpha, LIG3 DNA ligase 3 DNA ligase 3|ligase II, DNA, ATP-dependent|ligase III, DNA, ATP-dependent|polydeoxyribonucleotide synthase [ATP] 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on LIG3, check out the LIG3 Infographic

LIG3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LIG3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02741-1-100ul

100ul

$405

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