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Product Info Summary
| SKU: | A01035 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-DNA replication factor Cdt1 CDT1 Antibody
SKU/Catalog Number
A01035
Size
100ul
Form
Liquid
Description
Boster Bio Anti-DNA replication factor Cdt1 CDT1 Antibody catalog # A01035. Tested in WB,IHC,IP applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DNA replication factor Cdt1 CDT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01035)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Paxillin around the phosphorylation site of Y88.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01035 is reactive to Cdt1 in Human
Applications
A01035 is guaranteed for IP, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
61.51kDa
Background of Cdt1
4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1,000
IHC: 1:25-1:50
Validation Images & Assay Conditions
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Figure 2. Immunohistochemistry validation of CDT1 using Anti-DNA replication factor Cdt1 CDT1 Antibody (A01035).
Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CDT1 antibody. Counter stained with hematoxylin.For more protocol information of IHC
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Figure 1. Western blotting validation for Anti-DNA replication factor Cdt1 CDT1 Antibody A01035
Western blot analysis of CDT1 on Hela cell using anti-CDT1 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For Cdt1 (Source: Uniprot.org, NCBI)
Gene Name
Cdt1
Full Name
DNA replication factor Cdt1
Weight
61.51kDa
Superfamily
Cdt1 family
Alternative Names
chromatin licensing and DNA replication factor 1; DNA replication factor Cdt1; Double parked homolog; Double parked, Drosophila, homolog of; DUPRIS2 Cdt1|2610318F11Rik, AW545653, C76791, DUP, R, Ris2|chromatin licensing and DNA replication factor 1|DNA replication factor Cdt1|double parked homolog|retroviral insertion site 2 protein|retroviral integration site 1|retroviral integration site 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cdt1, check out the Cdt1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cdt1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DNA replication factor Cdt1 CDT1 Antibody (A01035)
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No publications found for A01035
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