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Product Info Summary
| SKU: | A06236 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-DNAJC13 Antibody
SKU/Catalog Number
A06236
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DNAJC13 Antibody (Catalog # A06236). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse.
Storage & Handling
DNAJC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-DNAJC13 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06236)
Host
Rabbit
Contents
DNAJC13 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
DNAJC13 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DNAJC13. The immunogen is located within amino acids 1940 - 1990 of DNAJC13.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist; this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.
Reactive Species
A06236 is reactive to DNAJC13 in Human, Mouse
Applications
A06236 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
254.415kDa
Background of DNAJC13
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans (1). It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles (2). DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DNAJC13 antibody can be used for detection of DNAJC13 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DNAJC13 in human heart tissue lysate with DNAJC13 antibody at 1 μg/ml.
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Immunohistochemistry of DNAJC13 in human heart tissue with DNAJC13 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For DNAJC13 (Source: Uniprot.org, NCBI)
Gene Name
DNAJC13
Full Name
DnaJ homolog subfamily C member 13
Weight
254.415kDa
Alternative Names
DnaJ (Hsp40) homolog, subfamily C, member 13; DnaJ domain-containing protein RME-8; dnaJ homolog subfamily C member 13; required for receptor-mediated endocytosis 8 DNAJC13 PARK21, RME8 DnaJ heat shock protein family (Hsp40) member C13 dnaJ homolog subfamily C member 13|DnaJ (Hsp40) homolog, subfamily C, member 13|DnaJ domain-containing protein RME-8|required for receptor-mediated endocytosis 8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DNAJC13, check out the DNAJC13 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DNAJC13: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DNAJC13 Antibody (A06236)
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No publications found for A06236
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Customer Reviews
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