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Product Info Summary
| SKU: | A08436 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-DRAK1 STK17A Antibody
SKU/Catalog Number
A08436
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DRAK1 STK17A Antibody (Catalog # A08436). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Storage & Handling
DRAK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-DRAK1 STK17A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08436)
Host
Rabbit
Contents
DRAK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. The immunogen is located within the first 50 amino acids of DRAK1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross responses to DRAK2, DAP or ZIP kinases.
Reactive Species
A08436 is reactive to STK17A in Human
Applications
A08436 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
46.558kDa
Background of DRAK1
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DRAK1 antibody can be used for detection of DRAK1 by Western blot at 1 μg/mL. An approximately 50 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DRAK1 in (A) MOLT4 and (B) A431 whole cell lysates with DRAK1 antibody at 1 μg/mL.
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Immunocytochemistry staining of MOLT4 cells using DRAK1 antibody at 2 μg/mL.
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Immunofluorescence of DRAK1 in Molt cells with DRAK1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For STK17A (Source: Uniprot.org, NCBI)
Gene Name
STK17A
Full Name
Serine/threonine-protein kinase 17A
Weight
46.558kDa
Superfamily
protein kinase superfamily
Alternative Names
DAP kinase-related apoptosis-inducing protein kinase 1; DRAK1; DRAK1death-associated protein kinase-related 1; EC 2.7.11.1; serine/threonine kinase 17a (apoptosis-inducing); serine/threonine kinase 17a; serine/threonine-protein kinase 17A; STK17A STK17A DRAK1 serine/threonine kinase 17a serine/threonine-protein kinase 17A|DAP kinase-related apoptosis-inducing protein kinase 1|death-associated protein kinase-related 1|serine/threonine kinase 17a (apoptosis-inducing)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STK17A, check out the STK17A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STK17A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DRAK1 STK17A Antibody (A08436)
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Customer Reviews
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