Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8)

Product Name

Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8)

View all Dystrophin Antibodies

SKU/Catalog Number

MA1037

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8) catalog # MA1037. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rabbit, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1037)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

MANDYS8

Isotype

Mouse IgG2b

Immunogen

Recombinant human dystrophin fragment.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

MA1037 is reactive to Dmd in Human, Mouse, Rabbit, Rat

Applications

MA1037 is guaranteed for IHC, WB Boster Guarantee

Background of Dystrophin

Dystrophin (DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons; the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain. overexpression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 0.2 ml of PBS buffer will yield a concentration of 500 ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 2-4μg/ml, Human, mouse, rabbit, rat, By Heat
Western blot, 1-2μg/ml, Human, mouse, rabbit, rat

Validation Images & Assay Conditions

Click image to see more details

Boster Kit Box

Gene/Protein Information For Dmd (Source: Uniprot.org, NCBI)

Alternative Names

BMDDXS272; CMD3B; DXS142; DXS164; DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142; dystrophin Dmd|DNADMD1|dystrophin|dystrophin|apodystrophin-3|apodystrophin-I|dystrophin, muscular dystrophy|dystrophin-related

For more info on Dmd, check out the Dmd Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Dmd: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

Take me to the Dmd Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis