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Product Info Summary
|Reactive Species:||Human, Mouse, Rabbit, Rat|
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Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8)
Boster Bio Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8) catalog # MA1037. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rabbit, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Dystrophin Dmd Antibody (Monoclonal, MANDYS8) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1037)
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Recombinant human dystrophin fragment.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins
MA1037 is reactive to Dmd in Human, Mouse, Rabbit, Rat
MA1037 is guaranteed for IHC, WB Boster Guarantee
Background of Dystrophin
Dystrophin (DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons; the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain. overexpression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 0.2 ml of PBS buffer will yield a concentration of 500 ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 2-4μg/ml, Human, mouse, rabbit, rat, By Heat
Western blot, 1-2μg/ml, Human, mouse, rabbit, rat
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For Dmd (Source: Uniprot.org, NCBI)
BMDDXS272; CMD3B; DXS142; DXS164; DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142; dystrophin Dmd|DNADMD1|dystrophin|dystrophin|apodystrophin-3|apodystrophin-I|dystrophin, muscular dystrophy|dystrophin-related*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on Dmd, check out the Dmd Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Dmd: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
No publications found for MA1037
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