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Product Info Summary
| SKU: | A08391 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC |
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Product info
Product Name
Anti-EAT-2 SH2D1B Antibody
SKU/Catalog Number
A08391
Size
100ul
Form
Liquid
Description
Boster Bio Anti-EAT-2 SH2D1B Antibody catalog # A08391. Tested in ELISA, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-EAT-2 SH2D1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08391)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human EAT-2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08391 is reactive to SH2D1B in Human
Applications
A08391 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
15.297kDa
Background of Sh2d1b
This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:40000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For SH2D1B (Source: Uniprot.org, NCBI)
Gene Name
SH2D1B
Full Name
SH2 domain-containing protein 1B
Weight
15.297kDa
Alternative Names
EAT2EAT-2; EWS/FLI1-activated transcript 2; SH2 domain containing 1B; SH2 domain-containing molecule EAT2; SH2 domain-containing protein 1B SH2D1B EAT2 SH2 domain containing 1B SH2 domain-containing protein 1B|EAT-2|EWS/FLI1-activated transcript 2|SH2 domain-containing molecule EAT2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SH2D1B, check out the SH2D1B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SH2D1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-EAT-2 SH2D1B Antibody (A08391)
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