Anti-EDG-2 (W45) LPAR1 Antibody

LPAR1/LPA1/EDG-2 antibody

Boster Bio Anti-EDG-2 (W45) LPAR1 Antibody catalog # A02782-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Rat.

Product Info Summary

SKU: A02782-1
Size: 100ul
Reactive Species: Human, Rat
Host: Rabbit
Application: IF, IHC, WB

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Product Name

Anti-EDG-2 (W45) LPAR1 Antibody

View all LPAR1/LPA1/EDG-2 Antibodies

SKU/Catalog Number

A02782-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-EDG-2 (W45) LPAR1 Antibody catalog # A02782-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-EDG-2 (W45) LPAR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02782-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human IRP-1 around the phosphorylation site of S711.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02782-1 is reactive to LPAR1 in Human, Rat

Applications

A02782-1 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

41.109kDa

Background of LPAR1/LPA1/EDG-2

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Cheung P.C.F., Biochem. J. 346:659-669(2000).
Lang T.M., Genomics 70:258-263(2000).
Ota T., Nat. Genet. 36:40-45(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200
IF: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For LPAR1 (Source: Uniprot.org, NCBI)

Gene Name

LPAR1

Full Name

Lysophosphatidic acid receptor 1

Weight

41.109kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

EDG2; edg-2; EDG2Lysophosphatidic acid receptor Edg-2; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor2,; GPCR26; GPR26; LPA receptor 1; LPA1; LPA-1; LPA1vzg-1; LPAR1; lysophosphatidic acid receptor 1; Mrec1.3; rec.1.3; ventricular zone gene 1; VZG1; vzg-1 LPAR1 EDG2, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1 lysophosphatidic acid receptor 1 lysophosphatidic acid receptor 1|LPA receptor 1|LPA-1|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2|lysophosphatidic acid receptor Edg-2|ventricular zone gene 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on LPAR1, check out the LPAR1 Infographic

LPAR1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for LPAR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02782-1-100ul

100ul

$405

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