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Product Info Summary
| SKU: | A15005 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-EFCAB4A CRACR2B Antibody
SKU/Catalog Number
A15005
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-EFCAB4A CRACR2B Antibody (Catalog # A15005). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
EFCAB4A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-EFCAB4A CRACR2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15005)
Host
Rabbit
Contents
EFCAB4A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A. The immunogen is located within amino acids 290 - 340 of EFCAB4A.
Reactive Species
A15005 is reactive to EFCAB4A in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
45.0 kDa
Background of EFCAB4A
EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A15005 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.
Specific Publications For Anti-EFCAB4A CRACR2B Antibody (A15005)
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