Product Info Summary
SKU: | A03844 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-ERAB HSD17B10 Antibody
SKU/Catalog Number
A03844
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ERAB HSD17B10 Antibody catalog # A03844. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ERAB HSD17B10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03844)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human ELOVL4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03844 is reactive to HSD17B10 in Human, Mouse, Rat
Applications
A03844 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
26.923kDa
Background of ERAB
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.
Zhang K., Nat. Genet. 27:89-93(2001).
Edwards A.O., Invest. Ophthalmol. Vis. Sci. 42:2652-2663(2001).
Ota T., Nat. Genet. 36:40-45(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-ERAB HSD17B10 Antibody A03844
Western blot analysis of ERAB polyclonal antibodyElectrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For HSD17B10 (Source: Uniprot.org, NCBI)
Gene Name
HSD17B10
Full Name
3-hydroxyacyl-CoA dehydrogenase type-2
Weight
26.923kDa
Superfamily
short-chain dehydrogenases/reductases (SDR) family
Alternative Names
17-beta-HSD 10; 17-beta-hydroxysteroid dehydrogenase 10; 17b-HSD10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; ABAD; amyloid-beta peptide binding alcohol dehydrogenase; CAMR; DUPXp11.22; EC 1.1.1.178; EC 1.1.1.35; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB3-hydroxyacyl-CoA dehydrogenase type-2; HADH2AB-binding alcohol dehydrogenase; hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II; hydroxysteroid (17-beta) dehydrogenase 10; mental retardation, X-linked, syndromic 10; MHBD; Mitochondrial ribonuclease P protein 2,3-hyd HSD17B10 17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD10MD, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1 hydroxysteroid 17-beta dehydrogenase 10 3-hydroxyacyl-CoA dehydrogenase type-2|3-hydroxy-2-methylbutyryl-CoA dehydrogenase|AB-binding alcohol dehydrogenase|amyloid-beta peptide binding alcohol dehydrogenase|endoplasmic reticulum-associated amyloid beta-peptide-binding protein|mitochondrial RNase P subunit 2|mitochondrial ribonuclease P protein 2|short chain L-3-hydroxyacyl-CoA dehydrogenase type 2|short chain type dehydrogenase/reductase XH98G2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on HSD17B10, check out the HSD17B10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for HSD17B10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ERAB HSD17B10 Antibody (A03844)
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No publications found for A03844
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Customer Reviews
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