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Product Info Summary
| SKU: | M01809 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-ERM ETV5 Monoclonal Antibody
SKU/Catalog Number
M01809
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ERM ETV5 Monoclonal Antibody catalog # M01809. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ERM ETV5 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01809)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
3H3
Isotype
IgG
Immunogen
Purified recombinant fragment of human ERM expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01809 is reactive to ETV5 in Human
Applications
M01809 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.838kDa
Background of ETV5/ERM
Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:10000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-ERM ETV5 Monoclonal Antibody M01809
Western Blot (WB) analysis using ERM Monoclonal Antibody against Jurkat (1)Protein Target Info & Infographic
Gene/Protein Information For ETV5 (Source: Uniprot.org, NCBI)
Gene Name
ETV5
Full Name
ETS translocation variant 5
Weight
57.838kDa
Superfamily
ETS family
Alternative Names
ERM; ERMEts-related protein ERM; ETS translocation variant 5; ets variant 5; ets variant gene 5 (ets-related molecule); ets-related molecule; ETV5 ETV5 ERM ETS variant transcription factor 5 ETS translocation variant 5|ETS variant 5|ets-related molecule|ets-related protein ERM
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ETV5, check out the ETV5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ETV5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ERM ETV5 Monoclonal Antibody (M01809)
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No publications found for M01809
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Customer Reviews
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Customer Q&As
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