Anti-Exportin-T XPOT Antibody

Product Name

Anti-Exportin-T XPOT Antibody

View all Exportin-T Antibodies

SKU/Catalog Number

A08486

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Exportin-T XPOT Antibody catalog # A08486. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Exportin-T XPOT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08486)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human RGL2 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08486 is reactive to XPOT in Human, Mouse, Rat

Applications

A08486 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

109.964kDa

Background of Exportin-T

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

Loftus B.J., Genomics 60:295-308(1999).
Wang Y., J. Immunol. 169:1102-1109(2002).
Pang T., J. Biol. Chem. 277:43771-43777(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Exportin-T XPOT Antibody A08486

Western blot analysis of extracts of various cell lines

Gene/Protein Information For XPOT (Source: Uniprot.org, NCBI)

Alternative Names

exportin(tRNA); exportin, tRNA (nuclear export receptor for tRNAs); exportin-T; tRNA exportin; XPO3 XPOT XPO3 exportin for tRNA exportin-T|exportin(tRNA)|exportin, tRNA (nuclear export receptor for tRNAs)|tRNA exportin

For more info on XPOT, check out the XPOT Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for XPOT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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