Product Info Summary
SKU: | A03662S1149 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IP, IHC, ICC, WB |
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Product info
Product Name
Anti-FANCA (phospho-S1149) Antibody
View all FACA/FANCA Antibodies
SKU/Catalog Number
A03662S1149
Size
100ul
Form
Liquid
Description
Boster Bio Anti-FANCA (phospho-S1149) Antibody catalog # A03662S1149. Tested in WB,IHC,ICC,IP applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FANCA (phospho-S1149) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03662S1149)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human KCNQ4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03662S1149 is reactive to FANCA in Human, Mouse, Rat
Applications
A03662S1149 is guaranteed for IP, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
162.775kDa
Background of FACA/FANCA
Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.
Kubisch C., Cell 96:437-446(1999).
Gregory S.G., Nature 441:315-321(2006).
Selyanko A.A., J. Physiol. (Lond.) 522:349-355(2000).<
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
ICC: 1:50-1:200
IP: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of FANCA using Anti-FANCA (phospho-S1149) Antibody (A03662S1149).
Immunohistochemistry (IHC) analyzes of p-FANCA (S1149) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibodyClick image to see more details
Figure 1. Western blotting validation for Anti-FANCA (phospho-S1149) Antibody A03662S1149
Western blot (WB) analysis of p-FANCA (S1149) polyclonal antibody at 1:500 dilutionLane1:HepG2 cell lysate treated with EGF(0.1ng/ML
Protein Target Info & Infographic
Gene/Protein Information For FANCA (Source: Uniprot.org, NCBI)
Gene Name
FANCA
Full Name
Fanconi anemia group A protein
Weight
162.775kDa
Alternative Names
FA; FA1; FAA; FAAMGC75158; FACA; FACAFanconi anemia group A protein; FAH; FA-H; FANCA; FANCH; Fanconi anemia, complementation group A; Fanconi anemia, complementation group H; Fanconi anemia, type 1; Protein FACA FANCA FA, FA-H, FA1, FAA, FACA, FAH, FANCH FA complementation group A Fanconi anemia group A protein|Fanconi anemia complementation group A|Fanconi anemia, complementation group H|Fanconi anemia, type 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FANCA, check out the FANCA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FANCA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FANCA (phospho-S1149) Antibody (A03662S1149)
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No publications found for A03662S1149
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