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Product Info Summary
| SKU: | M01956 |
|---|---|
| Size: | 100ug/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody
View all Ferritin Light Chain Antibodies
SKU/Catalog Number
M01956
Size
100ug/vial
Form
Liquid
Description
Boster Bio Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody (Catalog # M01956). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Cite This Product
Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01956)
Host
Mouse
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Clonality
Monoclonal
Clone Number
Clone: FTL/1389
Isotype
IgG1, kappa
Immunogen
Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M01956 is reactive to FTL in Human
Applications
M01956 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
20.02kDa
Background of Ferritin Light Chain
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Reconstitute with distilled water.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA (For coating, order antibody without BSA)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.
Validation Images & Assay Conditions
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Western Blot analysis of human HeLa cell lysate using Anti-Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1389).
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SDS-PAGE analysis purified Anti-Ferritin, Light Chain Mouse Monoclonal Antibody (FTL/1389). Confirmation of integrity and purity of antibody
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Western Blot analysis of kidney tissue lysate using Anti-Ferritin, Light Chain Monoclonal Antibody (FTL/1389).
Protein Target Info & Infographic
Gene/Protein Information For FTL (Source: Uniprot.org, NCBI)
Gene Name
FTL
Full Name
Ferritin light chain
Weight
20.02kDa
Superfamily
ferritin family
Alternative Names
Ferritin L subunit; ferritin L-chain; ferritin light chain; ferritin light polypeptide-like 3; ferritin, light polypeptide; MGC71996; NBIA3 FTL LFTD, NBIA3 ferritin light chain ferritin light chain|epididymis secretory sperm binding protein|ferritin L subunit|ferritin L-chain|ferritin light polypeptide-like 3|ferritin, light polypeptide
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FTL, check out the FTL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FTL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ferritin, Light Chain (FTL) (Microglia Marker) Monoclonal Antibody (M01956)
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No publications found for M01956
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