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Product Info Summary
| SKU: | A06977 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, ICC, WB |
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Product info
Product Name
Anti-FKBP6 Antibody
SKU/Catalog Number
A06977
Size
100ul
Form
Liquid
Description
Boster Bio Anti-FKBP6 Antibody catalog # A06977. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FKBP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06977)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human BMP10.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06977 is reactive to FKBP6 in Human, Mouse, Rat
Applications
A06977 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
37.214kDa
Background of FKBP6
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For FKBP6 (Source: Uniprot.org, NCBI)
Gene Name
FKBP6
Full Name
Inactive peptidyl-prolyl cis-trans isomerase FKBP6
Weight
37.214kDa
Superfamily
FKBP6 family
Alternative Names
36 kDa FKBP; EC 5.2.1.8; FK506 binding protein 6, 36kDa; FK506-binding protein 6 (36kD); FK506-binding protein 6; FKBP-36; FKBP36MGC87179; FKBP-6; Immunophilin FKBP36; peptidyl-prolyl cis-trans isomerase FKBP6,36 kDa FK506-binding protein; PPIase FKBP6; PPIase; rotamase FKBP6 FKBP36 FKBP prolyl isomerase family member 6 (inactive) inactive peptidyl-prolyl cis-trans isomerase FKBP6|36 kDa FKBP|FK506 binding protein 6, 36kDa|FK506-binding protein 6|FKBP prolyl isomerase 6|PPIase FKBP6|immunophilin FKBP36|inactive PPIase FKBP6|peptidyl-prolyl cis-trans isomerase FKBP6|rotamase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FKBP6, check out the FKBP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FKBP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FKBP6 Antibody (A06977)
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No publications found for A06977
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