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Product Info Summary
| SKU: | M04495-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Monkey, Mouse |
| Host: | Mouse |
| Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Forkhead box protein D3 FoxD3 Monoclonal Antibody
SKU/Catalog Number
M04495-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Forkhead box protein D3 FoxD3 Monoclonal Antibody catalog # M04495-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Forkhead box protein D3 FoxD3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04495-1)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
5G9
Isotype
IgG
Immunogen
Purified recombinant fragment of human FoxD3 expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
M04495-1 is reactive to Foxd3 in Human, Monkey, Mouse
Applications
M04495-1 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
46.345kDa
Background of Foxd3
Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
Validation Images & Assay Conditions
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Figure 2. Immunohistochemistry validation of FOXD3 using Anti-Forkhead box protein D3 FoxD3 Monoclonal Antibody (M04495-1).
Immunohistochemistry (IHC) analysis of paraffin-embedded Lung Cancer Tissues (left) and ovarian cancer tissues (right) with DAB staining using FoxD3 Monoclonal Antibody.For more protocol information of IHC
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Figure 1. Western blotting validation for Anti-Forkhead box protein D3 FoxD3 Monoclonal Antibody M04495-1
Western Blot (WB) analysis using FoxD3 Monoclonal Antibody against NTERA-2 (1)Protein Target Info & Infographic
Gene/Protein Information For Foxd3 (Source: Uniprot.org, NCBI)
Gene Name
Foxd3
Full Name
Forkhead box protein D3
Weight
46.345kDa
Alternative Names
Forkhead box protein D3 Foxd3|CWH3, Gen, Genesis, Hfh2|forkhead box D3|forkhead box protein D3|HFH-2|HNF-3/forkhead homolog 2|HNF3/FH transcription factor genesis|hepatocyte nuclear factor 3 forkhead homolog 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Foxd3, check out the Foxd3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Foxd3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Forkhead box protein D3 FoxD3 Monoclonal Antibody (M04495-1)
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No publications found for M04495-1
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