Anti-Forkhead box protein P3 FOXP3 Antibody

Foxp3 antibody

Boster Bio Anti-Forkhead box protein P3 FOXP3 Antibody catalog # A00011-1. Tested in ICC,Flow Cytometry applications. This antibody reacts with Human. Cited in 5 publication(s).

Product Info Summary

SKU: A00011-1
Size: 100ul
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry, ICC

Product Name

Anti-Forkhead box protein P3 FOXP3 Antibody

View all Foxp3 Antibodies

SKU/Catalog Number

A00011-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Forkhead box protein P3 FOXP3 Antibody catalog # A00011-1. Tested in ICC,Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Forkhead box protein P3 FOXP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00011-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Clone Number

PI9-17

Isotype

IgG

Immunogen

Synthesized peptide derived from human Neu around the phosphorylation site of Y1221/Y1222.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Weakly cross-reacts with dog p53.

Reactive Species

A00011-1 is reactive to Foxp3 in Human

Applications

A00011-1 is guaranteed for Flow Cytometry, ICC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

47.346kDa

Background of Foxp3

Anti-Glycogen Synthase 1 pS641 antibody is validated by IHC, Western Blot and ELISA. Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephosphorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3 that mainly functions to phosphorylate muscle glycogen synthase. This antibody is specific for the phosphorylated form of GS at S641. Phosphorylation of GS at S641 has been associated with Antiphospholipid Antibody Syndrome.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ICC: 1:50-1:200
FC: 1:50-1:100

Validation Images & Assay Conditions

Gene/Protein Information For Foxp3 (Source: Uniprot.org, NCBI)

Gene Name

Foxp3

Full Name

Forkhead box protein P3

Weight

47.346kDa

Alternative Names

AIID; AIIDMGC141961; human foxp3; mouse foxp3; DIETER; forkhead box P3; Forkhead Box Protein P3; foxp3 ihc; foxp3 paraffin; FoxP3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked; IPEX; JM2; MGC141961; MGC141963; PIDX; PIDXMGC141963; SCURFIN; XPID; XPIDpolyendocrinopathy, enteropathy, X-linked Foxp3|JM2, scu, scurfin, sf|forkhead box P3|forkhead box protein P3|scurfy

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Foxp3, check out the Foxp3 Infographic

Foxp3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Foxp3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00011-1 has been cited in 5 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

IL-35 improves Treg-mediated immune suppression in atherosclerotic mice

Decreased FOXP3+ and GARP+ Tregs to neoadjuvant chemotherapy associated with favorable prognosis in advanced gastric cancer

Wang B, Dai S, Dong Z, Sun Y, Song X, Guo C, Zhu F, Wang Q, Zhang L. Plos One. 2014 Jan 30;9(1):E87787. Doi: 10.1371/Journal.Pone.0087787. Ecollection 2014. The Modulation Of Endoplasmic Reticulum Stress By Chemical Chaperone Upregulates Immune Ne...

Hu M, Li K, Maskey N, Xu Z, Peng C, Wang B, Li Y, Yang G. Int J Clin Exp Pathol. 2014 Jul 15;7(8):4685-94. Ecollection 2014. Decreased Intratumoral Foxp3 Tregs And Increased Dendritic Cell Density By Neoadjuvant Chemotherapy Associated With Favora...

Gong T, Wang Cf, Yuan Jr, Li Y, Gu Jf, Zhao Bj, Zhang L, Jia Xb, Feng L, Liu Sl. Evid Based Complement Alternat Med. 2015;2015:630760. Doi: 10.1155/2015/630760. Epub 2015 May 3. Inhibition Of Tumor Growth And Immunomodulatory Effects Of Flavonoids...

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Order DetailsPrice
A00011-1-100ul

100ul

$405

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