Product Info Summary
SKU: | A00842 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Frataxin, mitochondrial FXN Antibody
SKU/Catalog Number
A00842
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Frataxin, mitochondrial FXN Antibody catalog # A00842. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Frataxin, mitochondrial FXN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00842)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human DOT1L protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00842 is reactive to FXN in Human, Mouse, Rat
Applications
A00842 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
23.135kDa
Background of Frataxin
Two elongation factors (EF) EF-Tu and EF-2 participate in the elongation phase during protein biosynthesis on the ribosome and their functional cycles depend on GTP binding and its hydrolysis. EF-Tu (also designated mitochondrial precursor p43) and EF-2 are multidomain GTPases with essential functions in translation, and they both bind to the same site on the ribosome where their low intrinsic GTPase activities are strongly stimulated. EF-Tu plays a central role in the fast and accurate delivery of aminoacyl-tRNAs to the translating ribosome. In addition, EF-Tu protects the aminoester bond against hydrolysis until a correct match between the codon on mRNA and the anticodon on tRNA can be achieved. EF-2 supports the translocation of tRNAs and of mRNAs on the ribosome so that a new codon can be exposed for decoding.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Frataxin
Protein Target Info & Infographic
Gene/Protein Information For FXN (Source: Uniprot.org, NCBI)
Gene Name
FXN
Full Name
Frataxin, mitochondrial
Weight
23.135kDa
Superfamily
frataxin family
Alternative Names
CyaY; EC 1.16.3.1; FA; FARRmitochondrial; frataxin; Friedreich ataxia protein; Friedreich ataxia; Fxn; X25MGC57199 FXN CyaY, FA, FARR, FRDA, X25 frataxin frataxin, mitochondrial|Friedreich ataxia protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FXN, check out the FXN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FXN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Frataxin, mitochondrial FXN Antibody (A00842)
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No publications found for A00842
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