Click image to see more details
Product Info Summary
| SKU: | A15565 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-FRMPD4 TMEM94 Antibody
SKU/Catalog Number
A15565
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-FRMPD4 TMEM94 Antibody (Catalog # A15565). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
FRMPD4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-FRMPD4 TMEM94 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A15565)
Host
Rabbit
Contents
FRMPD4 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
FRMPD4 antibody was raised against an 18 amino acid synthetic peptide from near the center of human FRMPD4. The immunogen is located within amino acids 620 - 670 of FRMPD4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TYW2 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW2 are known to exist; this antibody will detect both isoforms
Reactive Species
A15565 is reactive to TMEM94 in Human
Applications
A15565 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
151.151kDa
Background of TMEM94
The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD4, also known as Preso, also contains another protein interaction domain termed WW (domain with two conserved Trp residues) at its amino terminus. It was identified through a yeast two-hybrid screen using the PDZ domain of PSD-95 as bait and is highly expressed in multiple regions of the brain and is enriched in the postsynaptic density (PSD) fractions. Overexpression of FRMPD4 in cultured hippocampal neurons significantly increased the linear density of dendritic spines without changing their length and width; conversely, knockdown experiments using RNAi caused a decrease in spine density, indicating FRMPD4 positively regulates dendritic spine density but not morphology. The decreased level of FRMPD4 also resulted in reduced levels of excitatory synaptic transmission, suggesting that FRMPD4 is required for maintenance of excitatory synaptic transmission.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FRMPD4 antibody can be used for detection of FRMPD4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of FRMPD4 in SK-N-SH cell lysate with FRMPD4 antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunohistochemistry of FRMPD4 in human brain tissue with FRMPD4 antibody at 5 μg/mL.
Click image to see more details
Immunofluorescence of FRMPD4 in human brain tissue with FRMPD4 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM94 (Source: Uniprot.org, NCBI)
Gene Name
TMEM94
Full Name
Transmembrane protein 94
Weight
151.151kDa
Alternative Names
Transmembrane protein 94 TMEM94 IDDCDF, KIAA0195 transmembrane protein 94 transmembrane protein 94
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM94, check out the TMEM94 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM94: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FRMPD4 TMEM94 Antibody (A15565)
Hello CJ!
No publications found for A15565
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-FRMPD4 TMEM94 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-FRMPD4 TMEM94 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
