Anti-GADD45GIP1 Antibody

Product Name

Anti-GADD45GIP1 Antibody

View all CRIF1 Antibodies

SKU/Catalog Number

A06696-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-GADD45GIP1 Antibody catalog # A06696-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GADD45GIP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06696-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human GADD45GIP1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06696-1 is reactive to GADD45GIP1 in Human, Mouse, Rat

Applications

A06696-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

25.384kDa

Background of CRIF1

Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Goernemann J., Virology 303:69-78(2002).
Chung H.K., J. Biol. Chem. 278:28079-28088(2003).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

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Western blot (WB) analysis of GADD45GIP1 polyclonal antibody at 1:500 dilution
Line1:Hela whole cell lysate
Line2:PC12 whole cell lysate
Line3:sp20 whole cell lysate

Gene/Protein Information For GADD45GIP1 (Source: Uniprot.org, NCBI)

Alternative Names

CKBBP2; CKII beta-associating protein; CR6 interacting factor 1; CRIF1p53-responsive gene 6 protein; growth arrest and DNA damage-inducible proteins-interacting protein 1; growth arrest and DNA-damage-inducible, gamma interacting protein 1; MGC4667; MGC4758; papillomavirus L2 interacting nuclear protein 1; Papillomavirus L2-interacting nuclear protein 1; Plinp1; PLINP-1CKII beta binding protein 2; PRG6CR6-interacting factor 1 GADD45GIP1 CKBBP2, CKbetaBP2, CRIF1, MRP-L59, PLINP, PLINP-1, PRG6, Plinp1 GADD45G interacting protein 1 growth arrest and DNA damage-inducible proteins-interacting protein 1|39S ribosomal protein L59, mitochondrial|CKII beta binding protein 2|CKII beta-associating protein|CR6 interacting factor 1|growth arrest and DNA-damage-inducible, gamma interacting protein 1|growth arrest- and DNA damage-inducible GADD45G-interacting protein|mitochondrial large ribosomal subunit protein CRIF1|mitochondrial large ribosomal subunit protein mL64|p53-responsive gene 6 protein|papillomavirus L2 interacting nuclear protein 1

For more info on GADD45GIP1, check out the GADD45GIP1 Infographic

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In this infographic, you will see the following information for GADD45GIP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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