Product Info Summary
SKU: | A07082 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-GCSH Antibody
SKU/Catalog Number
A07082
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GCSH Antibody catalog # A07082. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GCSH Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07082)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human TRIM3
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07082 is reactive to GCSH in Human, Mouse, Rat
Applications
A07082 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
18.885kDa
Background of GCSH
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
Shirane M, et al. (1999) J Biol Chem; 274(40): 28169-74
Karin, M. and Ben-Neriah, Y. (2000) Annu. Rev. Immunol. ;18, 621-663.
Chen, Z.J. et al. (1996) Cell; 84, 853-862.
Brown, K. et al. (1995) Science; 267, 1485-1488.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-GCSH Antibody A07082
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For GCSH (Source: Uniprot.org, NCBI)
Gene Name
GCSH
Full Name
Glycine cleavage system H protein, mitochondrial
Weight
18.885kDa
Superfamily
GcvH family
Alternative Names
GCE; glycine cleavage system H protein, mitochondrial; glycine cleavage system protein H (aminomethyl carrier); lipoic acid-containing protein; mitochondrial glycine cleavage system H-protein; NKH GCSH GCE, NKH glycine cleavage system protein H glycine cleavage system H protein, mitochondrial|glycine cleavage system protein H (aminomethyl carrier)|lipoic acid-containing protein|mitochondrial glycine cleavage system H-protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GCSH, check out the GCSH Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GCSH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GCSH Antibody (A07082)
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No publications found for A07082
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