Product Info Summary
SKU: | A01162-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Glucosylceramidase GBA Antibody
View all Glucosylceramidase/GBA Antibodies
SKU/Catalog Number
A01162-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Glucosylceramidase GBA Antibody catalog # A01162-1. Tested in WB,IHC applications. This antibody reacts with Human,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Glucosylceramidase GBA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01162-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human DAPK1 (Phospho-Ser308)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01162-1 is reactive to GBA in Human, Rat
Applications
A01162-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
59.716kDa
Background of Glucosylceramidase/GBA
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.
George A.L. Jr., Ann. Neurol. 31:131-137(1992).
Wang J., Biochem. Biophys. Res. Commun. 182:794-801(1992).
Tsujino A., Proc. Natl. Acad. Sci. U.S.A. 100:7377-7382(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:5,000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of GBA using Anti-Glucosylceramidase GBA Antibody (A01162-1).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-GBA antibody. Counter stained with hematoxylin.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-Glucosylceramidase GBA Antibody A01162-1
Western blot analysis of GBA on diffewrent cells lysates using anti-GBA antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For GBA (Source: Uniprot.org, NCBI)
Gene Name
GBA
Full Name
Lysosomal acid glucosylceramidase
Weight
59.716kDa
Superfamily
glycosyl hydrolase 30 family
Alternative Names
Acid beta-glucosidase; Alglucerase; beta-glucocerebrosidase; D-glucosyl-N-acylsphingosine glucohydrolase; EC 3.2.1.45; GBA; GBA1; GC; GCB; GLUC; glucosidase, beta, acid; glucosidase, beta; acid (includes glucosylceramidase); Glucosylceramidase; Imiglucerase; lysosomal glucocerebrosidase GBA GBA1, GCB, GLUC glucosylceramidase beta lysosomal acid glucosylceramidase|D-glucosyl-N-acylsphingosine glucohydrolase|SGTase|acid beta-glucosidase|alglucerase|beta-GC|beta-glucocerebrosidase|cholesterol glucosyltransferase|cholesteryl-beta-glucosidase|glucosidase, beta, acid|glucosylceramidase-like protein|imiglucerase|lysosomal acid GCase|lysosomal glucocerebrosidase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GBA, check out the GBA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GBA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Glucosylceramidase GBA Antibody (A01162-1)
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No publications found for A01162-1
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Customer Reviews
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