Anti-GLUD1 Antibody

Product Name

Anti-GLUD1 Antibody

View all Glutamate Dehydrogenase Antibodies

SKU/Catalog Number

A01866

Size

100ul

Form

Liquid

Description

Boster Bio Anti-GLUD1 Antibody catalog # A01866. Tested in WB,IHC,ICC/IF,IP applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GLUD1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01866)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human RAD21.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01866 is reactive to GLUD1 in Human, Mouse, Rat

Applications

A01866 is guaranteed for IP, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

61.398kDa

Background of Glutamate Dehydrogenase

Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

McKay M.J., Genomics 36:305-315(1996).
Sadano H., Biochem. Biophys. Res. Commun. 267:418-422(2000).
Nomura N., DNA Res. 1:223-229(1994).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:100-1:200
ICC/IF: 1:50-1:200
IP: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For GLUD1 (Source: Uniprot.org, NCBI)

Alternative Names

EC 1.4.1; EC 1.4.1.3; GDH 1; GDH; GDH1; GLUD; glutamate dehydrogenase (NAD(P)+); Glutamate Dehydrogenase 1; glutamate dehydrogenase 1, mitochondrial; MGC132003 GLUD1 GDH, GDH1, GLUD glutamate dehydrogenase 1 glutamate dehydrogenase 1, mitochondrial|epididymis secretory sperm binding protein|epididymis tissue sperm binding protein Li 18mP|glutamate dehydrogenase (NAD(P)+)

For more info on GLUD1, check out the GLUD1 Infographic

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In this infographic, you will see the following information for GLUD1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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