Product Info Summary
SKU: | A12882 |
---|---|
Size: | 100μl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-GPR114 Antibody
SKU/Catalog Number
A12882
Size
100μl
Form
Liquid
Description
Boster Bio Anti-GPR114 Antibody catalog # A12882. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GPR114 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12882)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
2H4
Isotype
IgG
Immunogen
Synthesized peptide derived from the Internal region of human GPR114. at AA rangle: 70-150
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A12882 is reactive to ADGRG5 in Human
Applications
A12882 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
59kDa
Background of GPR114
COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Western Blot (WB) analysis of COLO205 cells using GPR114 Polyclonal antibody.
Protein Target Info & Infographic
Gene/Protein Information For ADGRG5 (Source: Uniprot.org, NCBI)
Gene Name
ADGRG5
Full Name
Adhesion G-protein coupled receptor G5
Weight
59kDa
Superfamily
G-protein coupled receptor 2 family
Alternative Names
G protein-coupled receptor 114; G protein-coupled receptor PGR27; GPR114; G-protein coupled receptor PGR27; PGR27; PGR27G-protein coupled receptor 114; probable G-protein coupled receptor 114 ADGRG5 GPR114, PGR27 adhesion G protein-coupled receptor G5 adhesion G-protein coupled receptor G5|G protein-coupled receptor 114|G protein-coupled receptor PGR27|probable G-protein coupled receptor 114
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ADGRG5, check out the ADGRG5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ADGRG5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GPR114 Antibody (A12882)
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No publications found for A12882
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