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Product Info Summary
| SKU: | A11787-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-GPR139 Antibody
SKU/Catalog Number
A11787-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GPR139 Antibody catalog # A11787-1. Tested in ELISA, IF, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GPR139 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11787-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GPR139
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A11787-1 is reactive to GPR139 in Human, Mouse, Rat
Applications
A11787-1 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
40.679kDa
Background of GPR139
Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability By similarity. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors.
Ota T., Nat. Genet. 36:40-45(2004).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Sjoeblom T., Science 314:268-274(2006)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Validation Images & Assay Conditions
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Figure 1. Western blotting validation for Anti-GPR139 Antibody A11787-1
Western Blot (WB) analysis of K562 cells using GPR139 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For GPR139 (Source: Uniprot.org, NCBI)
Gene Name
GPR139
Full Name
Probable G-protein coupled receptor 139
Weight
40.679kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
G protein-coupled receptor 139; G(q)-coupled orphan receptor GPRg1; GPR139; GPRg1; G-protein-coupled receptor PGR3; PGR3; PGR3G protein-coupled receptor PGR3; probable G-protein coupled receptor 139 GPR139 GPRg1, PGR3 G protein-coupled receptor 139 probable G-protein coupled receptor 139|G protein-coupled receptor PGR3|g(q)-coupled orphan receptor GPRg1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GPR139, check out the GPR139 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GPR139: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GPR139 Antibody (A11787-1)
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No publications found for A11787-1
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Customer Reviews
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