Anti-Granzyme K GZMK Antibody

Product Name

Anti-Granzyme K GZMK Antibody

View all Granzyme K Antibodies

SKU/Catalog Number

A06281

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Granzyme K GZMK Antibody catalog # A06281. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Granzyme K GZMK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06281)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Granzyme K. at AA rangle: 30-110

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06281 is reactive to GZMK in Human, Mouse, Rat

Applications

A06281 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

28.882kDa

Background of Granzyme K

APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using Granzyme K Polyclonal antibody.

Gene/Protein Information For GZMK (Source: Uniprot.org, NCBI)

Alternative Names

EC 3.4.21; EC 3.4.21.-; EC 3.4.21.4; Fragmentin-3; Granzyme 3; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); Granzyme K; Granzyme-3; Granzyme-K; GZMK; NK-Tryp-2; NK-Tryptase-2; PRSS; TRYP2; TRYP2granzyme-3; Tryptase II GZMK TRYP2 granzyme K granzyme K|NK-Tryp-2|NK-tryptase-2|fragmentin-3|granzyme 3|granzyme K (granzyme 3; tryptase II)|granzyme K (serine protease, granzyme 3; tryptase II)|tryptase II

For more info on GZMK, check out the GZMK Infographic

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In this infographic, you will see the following information for GZMK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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