Granzyme K Antibodies

AND GZMK ELISA kits, Granzyme K Proteins

Many biological assays use antibodies to detect Granzyme K, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Granzyme K in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Granzyme K antibodies...

We validate the specificity of these antibodies to Granzyme K by testing them on tissues known to express GZMK positively and negatively. Browse below to find the GZMK antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Granzyme K? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the GZMK IHC Guide

GZMK Infographic by Boster Bio

All GZMK Products

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Product

Figures

Specificity

Applications

Price

Anti-Granzyme K/GZMK Antibody

Human

IHC

$370
Cat # A06281-2
100 μg/vial

Anti-Granzyme K (H85) GZMK Antibody

Immunohistochemistry (IHC) analyzes of Granzyme K (H85) pAb in paraffin-embedded human breast carcinoma tissue at 1:100

Human, Mouse, Rat

IF, IHC

$405
Cat # A06281-1
100ul

Granzyme K (GZMK) (NM_002104) Human Over-expression Lysate

Human

$628
Cat # LS003003
20 µg, 100 µg

Human GZMK Recombinant Protein

SDS-PAGE

$250
Cat # PROTP49863
Starting from 10ug

Anti-Granzyme K GZMK Antibody

Western Blot (WB) analysis of specific cells using Granzyme K Polyclonal antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A06281
100μl

GZMK Overview

Facts about Granzyme K.

GZMK 3D structure. Source: alphafold

Granzyme K (GZMK)

Gene Information

Human
Gene Name:	GZMK
Uniprot:	P49863
Entrez:	3003

Family

Belongs to:

peptidase S1 family

Alternative Names

EC 3.4.21; EC 3.4.21.-; EC 3.4.21.4; Fragmentin-3; Granzyme 3; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); Granzyme K; Granzyme-3; Granzyme-K; GZMK; NK-Tryp-2; NK-Tryptase-2; PRSS; TRYP2; TRYP2granzyme-3; Tryptase II

Molecular Weight

Mass (kDA):
28.882 kDA

Genomic Context


Human

Location:	5q11.2
Sequence:	5; NC_000005.10 (55024256..55034570)

Tissue Specificity

Expressed in lung, spleen, thymus and peripheral blood leukocytes.

Subcellular Localizations

Secreted. Cytoplasmic granule.

Diseases

Neoplasms
Inflammation
Melanoma
Malignant Neoplasms
Leukemia
Halo Nevus
Autoimmunity
Sclerosis
Neoplasm Metastasis
Lung Diseases, Interstitial
Immunologic Deficiency Syndromes
Endometritis

Cytomegalovirus Infections
Acute Promyelocytic Leukemia
L1 Acute Lymphoblastic Leukemia
Marfan Syndrome
Influenza
Hereditary Diseases

Pathways

Immune Response
Cell Death
Secretion
Cell Adhesion
Cell Proliferation
Gene Silencing
Type I Interferon Production
Dna Amplification
Cytokine Production
T Cell Differentiation

Cell Cycle
Cell Differentiation
Exocytosis
Cell Recognition

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GZMK

References

PMID: 7758581 by Przetak M.M., et al. Cloning of cDNA for human granzyme 3.

PMID: 8656064 by Sayers T.J., et al. Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3.