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Product Info Summary
| SKU: | A03167 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-GRIP1 Antibody
SKU/Catalog Number
A03167
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-GRIP1 Antibody (Catalog # A03167). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
GRIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-GRIP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03167)
Host
Rabbit
Contents
GRIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal GRIP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GRIP1. The immunogen is located within the last 50 amino acids of GRIP1.
Reactive Species
A03167 is reactive to GRIP1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
122.4 kDa
Background of GRIP1
Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03167 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of GRIP1 in 293 cell lysate with GRIP1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of GRIP1 in rat brain tissue with GRIP1 antibody at 2.5 μg/ml.
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Immunofluorescence of GRIP1 in rat brain tissue with GRIP1 antibody at 20 μg/ml.
Specific Publications For Anti-GRIP1 Antibody (A03167)
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