Product Info Summary
| SKU: | A01462-2 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA (Cap) |
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Product info
Product Name
Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody
SKU/Catalog Number
A01462-2
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody catalog # A01462-2. Tested in ELISA applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01462-2)
Host
Rabbit
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
E. coli-derived humn GSTA1/A2/A3/A4/A5 recombinant protein (Position: A2-F222).
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
A01462-2 is reactive to GSTA1 in Human
Calculated molecular weight
25.6 kDa
Background of GSTA1
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01462-2 is guaranteed for ELISA (Cap) Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA Capture (Matched Antibody Pair), 2-8μg/ml
Validation Images & Assay Conditions
Click image to see more details
Boster Kit Box
Specific Publications For Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody (A01462-2)
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