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Product Info Summary
| SKU: | M01335-3 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Cow, Human, Primate |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, IHC-F, ICC |
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Product info
Product Name
Anti-Hu CD117 Purified KIT Monoclonal Antibody
View all CD117/c-kit Antibodies
SKU/Catalog Number
M01335-3
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD117 Purified KIT Monoclonal Antibody (Catalog# M01335-3). Tested in Flow Cytometry, IP, IHC-F, ICC application(s). This antibody reacts with Primate, Human, Cow.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD117 Purified KIT Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01335-3)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
104D2
Isotype
Mouse IgG1 kappa
Immunogen
MOLM-1 megakaryocytic cells. The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01335-3 is reactive to KIT in Cow, Human, Primate
Applications
M01335-3 is guaranteed for Flow Cytometry, IP, IHC-F, ICC Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
109.865kDa
Background of CD117/c-kit
CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For KIT (Source: Uniprot.org, NCBI)
Gene Name
KIT
Full Name
Mast/stem cell growth factor receptor Kit
Weight
109.865kDa
Superfamily
protein kinase superfamily
Alternative Names
CD117 antigen; CD117; ckit; c-kit; EC 2.7.10; EC 2.7.10.1; KIT; PBT; piebald trait; Proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; SCF R; SCFR; SCFRmast/stem cell growth factor receptor; soluble KIT variant 1; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein KIT C-Kit, CD117, MASTC, PBT, SCFR KIT proto-oncogene, receptor tyrosine kinase mast/stem cell growth factor receptor Kit|c-Kit protooncogene|p145 c-kit|piebald trait protein|proto-oncogene c-Kit|proto-oncogene tyrosine-protein kinase Kit|soluble KIT variant 1|tyrosine-protein kinase Kit|v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog|v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KIT, check out the KIT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KIT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD117 Purified KIT Monoclonal Antibody (M01335-3)
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No publications found for M01335-3
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