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Product Info Summary
| SKU: | M05615 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry, ICC |
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Product info
Product Name
Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody
View all ENPP-3/CD203c Antibodies
SKU/Catalog Number
M05615
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody (Catalog# M05615). Tested in Flow Cytometry, ICC application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05615)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
NP4D6
Isotype
Mouse IgG1
Immunogen
HEK-293 cells transfected with human CD203c. The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M05615 is reactive to ENPP3 in Human
Applications
M05615 is guaranteed for Flow Cytometry, ICC Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
100.124kDa
Background of ENPP-3/CD203c
CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml. Extracellular and intracellular staining.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ENPP3 (Source: Uniprot.org, NCBI)
Gene Name
ENPP3
Full Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
Weight
100.124kDa
Superfamily
nucleotide pyrophosphatase/phosphodiesterase family
Alternative Names
B10; CD203c antigen; CD203c; dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); ectonucleotide pyrophosphatase/phosphodiesterase 3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; ENPP3; ENPP-3; gp130RB13-6; NPP3; PD-IBETA; PDNP3; PDNP3B10; Phosphodiesterase I beta; Phosphodiesterase I/nucleotide pyrophosphatase 3; phosphodiesterase-I beta ENPP3 B10, CD203c, NPP3, PD-IBETA, PDNP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 ectonucleotide pyrophosphatase/phosphodiesterase family member 3|dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3)|gp130RB13-6|phosphodiesterase I/nucleotide pyrophosphatase 3|phosphodiesterase-I beta
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ENPP3, check out the ENPP3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ENPP3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD203c Purified ENPP3 Monoclonal Antibody (M05615)
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No publications found for M05615
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