Product Info Summary
SKU: | M00769-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, ICC |
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Product info
Product Name
Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody
SKU/Catalog Number
M00769-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody (Catalog# M00769-1). Tested in Flow Cytometry, ICC application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00769-1)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
4FR6D3
Isotype
Mouse IgG1 kappa
Immunogen
NIH 3T3 cells transfected with full length human CD334. The mouse monoclonal antibody 4FR6D3 reacts with an extracellular epitope of CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00769-1 is reactive to FGFR4 in Human
Applications
M00769-1 is guaranteed for Flow Cytometry, ICC Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
87.954kDa
Background of FGFR4
CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 2-6 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For FGFR4 (Source: Uniprot.org, NCBI)
Gene Name
FGFR4
Full Name
Fibroblast growth factor receptor 4
Weight
87.954kDa
Superfamily
protein kinase superfamily
Alternative Names
CD334 antigen; CD334; EC 2.7.10; EC 2.7.10.1; FGF R4; FGFR4; FGFR-4; fibroblast growth factor receptor 4; JTK2hydroxyaryl-protein kinase; MGC20292; protein-tyrosine kinase; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase FGFR4 CD334, JTK2, TKF fibroblast growth factor receptor 4 fibroblast growth factor receptor 4|hydroxyaryl-protein kinase|protein-tyrosine kinase|tyrosine kinase related to fibroblast growth factor receptor|tyrosylprotein kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FGFR4, check out the FGFR4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FGFR4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody (M00769-1)
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No publications found for M00769-1
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