Anti-Human CCKBR DyLight® 550 conjugated Antibody

Cholecystokinin-B R/CCKBR antibody

Boster Bio Anti-Human CCKBR DyLight® 550 conjugated Antibody catalog # A01677-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Product Info Summary

SKU: A01677-Dyl550
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry

Product Name

Anti-Human CCKBR DyLight® 550 conjugated Antibody

View all Cholecystokinin-B R/CCKBR Antibodies

SKU/Catalog Number

A01677-Dyl550

Size

100 μg/vial

Form

Liquid

Description

Boster Bio Anti-Human CCKBR DyLight® 550 conjugated Antibody catalog # A01677-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Cite This Product

Anti-Human CCKBR DyLight® 550 conjugated Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01677-Dyl550)

Host

Rabbit

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human CCKBR, which shares 80% and 90% amino acid (aa) sequence identity with mouse and rat CCKBR, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01677-Dyl550 is reactive to CCKBR in Human

Applications

A01677-Dyl550 is guaranteed for Flow Cytometry Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

48.419kDa

Background of Cholecystokinin-B R/CCKBR

The cholecystokinin B receptor, also known as CCKBR or CCK2, is a protein that in humans is encoded by the CCKBR gene. This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry, 1-3μg/1x106 cells

Validation Images & Assay Conditions

Gene/Protein Information For CCKBR (Source: Uniprot.org, NCBI)

Gene Name

CCKBR

Full Name

Gastrin/cholecystokinin type B receptor

Weight

48.419kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

CCK2 receptor; CCK2R; CCK2-R; CCK-B receptor; CCK-B; CCKBR; CCK-BR; CCKRB; cholecystokinin B receptor; Cholecystokinin-2 receptor; Cholecystokinin-B R; cholecystokinin-B receptor/gastrin receptor; CholecystokininBR; Cholecystokinin-BR; GASR; Gastrin Receptor; gastrin/cholecystokinin type B receptor CCKBR CCK-B, CCK2R, GASR cholecystokinin B receptor gastrin/cholecystokinin type B receptor|CCK-B receptor|CCK2 receptor|cholecystokinin-2 receptor|gastrin receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CCKBR, check out the CCKBR Infographic

CCKBR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CCKBR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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4 Customer Q&As for Anti-Human CCKBR DyLight® 550 conjugated Antibody

Question

Is a blocking peptide available for product anti-Human CCKBR DyLight® 550 conjugated antibody (A01677-Dyl550)?

Verified Customer

Verified customer

Asked: 2019-11-11

Answer

We do provide the blocking peptide for product anti-Human CCKBR DyLight® 550 conjugated antibody (A01677-Dyl550). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-11-11

Question

We are currently using anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 for human tissue, and we are satisfied with the Flow Cytometry results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on canine tissues as well?

Verified Customer

Verified customer

Asked: 2019-06-14

Answer

The anti-Human CCKBR DyLight® 550 conjugated antibody (A01677-Dyl550) has not been validated for cross reactivity specifically with canine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-06-14

Question

My lab would like to test anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 on human colon cancer for research purposes, then I may be interested in using anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2017-07-31

Answer

The products we sell, including anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2017-07-31

Question

Does anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 work for Flow Cytometry with colon cancer?

G. Edwards

Verified customer

Asked: 2014-12-23

Answer

According to the expression profile of colon cancer, CCKBR is highly expressed in colon cancer. So, it is likely that anti-Human CCKBR DyLight® 550 conjugated antibody A01677-Dyl550 will work for Flow Cytometry with colon cancer.

Boster Scientific Support

Answered: 2014-12-23

Order DetailsPrice
A01677-Dyl550

100μg

$515
A01677-Dyl550-carrier-free

Carrier Free

$515

Free Secondary Antibody

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A01677-Dyl550
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$515.00

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