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Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody
Boster Bio Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody catalog # A01490-Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Cite This Product
Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01490-Dyl488)
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins.
A01490-Dyl488 is reactive to NRXN1 in Human
A01490-Dyl488 is guaranteed for Flow Cytometry Boster Guarantee
Background of Nrxn1
Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Flow Cytometry, 1-3μg/1x106 cells
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For NRXN1 (Source: Uniprot.org, NCBI)
Neurexin 1 beta; NXR1B; NXRN1b NRXN1 Hs.22998, PTHSL2, SCZD17 neurexin 1 neurexin-1|neurexin I*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on NRXN1, check out the NRXN1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NRXN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
Specific Publications For Anti-Human Neurexin 1 DyLight® 488 conjugated NRXN1 Antibody (A01490-Dyl488)
No publications found for A01490-Dyl488
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